Having your cake and eating it too - a new target for sporozoite-neutralising mAbs.

• Tác giả: Ian A Cockburn, Colin J Jackson, Joe A Kaczmarski
• Ngôn ngữ: eng
• Ký hiệu phân loại: 809.008 History and description with respect to kinds of persons
• Thông tin xuất bản: England : Trends in parasitology , 2025
• Bộ sưu tập: NCBI
• ID: 489381

Tóm tắt

Current malaria vaccines provide suboptimal, waning protection. Dacon et al. identify a protective post-translationally modified epitope on Plasmodium sporozoites that is absent from current vaccines. This discovery deepens our understanding of Plasmodium biology and may inform the development of improved vaccines and complementary prophylactic monoclonal antibodies.