Đề kháng in vitro và đặc điểm vi khuẩn gây đợt kịch phát copd nhiễm khuẩn nhập viện tại bệnh viện đại học y dược thành phố hồ chí minh 2020

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Tác giả: Kiều Minh Lê, Tiến Dũng Lê, Xuân Sáng Trần

Ngôn ngữ: vie

Ký hiệu phân loại: 616.9041 Other diseases

Thông tin xuất bản: Tạp chí y học việt nam (tổng hội y học việt nam), 2022

Mô tả vật lý: 79-86

Bộ sưu tập: Metadata

ID: 489650

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Investigating characteristics and in-vitro resistance to bacteria causing acute exacerbations of COPD at HCMC University Medical Center 2020. Methods(:) 221 acute exacerbations of COPD patients were treated at HCMC University Medical Center from February 2019 to December 2020. Among them, 48 cas (22,75%) were determined to have positive sputum or BAL culture. Results(:) Gram-negative bacteria accounted for the majority (81.43%) compared to gram-positive bacteria (18.57%). The most common strains was K. pneumonia (25.7%), A. baumannii (21,43%), P. aeruginosae (17,14%). Gram-positive bacteria accounted for the minority (18.57%), with S. pneumonia (4.3%), Staphylococcus spp. (14.3%). S.pneumonia was high resistant to Penicillin và Macrolide. Staphylococcus spp. was not resistant to Linesolide. P.aeruginosa had relatively low( )resistance to Imipenem, meropenem, Amikacin. K.pneumoniae had relatively low resistance to Amikacin. A. baumannii was high resistant to all, only low resistant to Cefoperazol/sulbactam (20%). Conclusion(:) Gram- negative bacteria accounted for the majority compared to gram- positive bacteria. The most common strains was K. pneumonia, A. baumannii, P. aeruginosae, Staphylococcus spp. Bacteria caused AECOPD are multiform and increasing high antibiotic resistance.Khảo sát đặc điểm vi khuẩn và đề kháng in vitro vi khuẩn gây đợt kịch phát COPD tại Bệnh viện Đại học Y Dược TPHCM 2020 Phương pháp(:) 221 bệnh nhân người lớn đợt kịch phát COPD điều trị tại Bệnh viện Đại học Y Dược TPHCM thời gian 02/2019 đến 12/2020, gồm 48 cas ( 22,75%) bệnh nhân có kết quả cấy đàm hay dịch rửa phế quản (BAL) tìm thấy vi khuẩn gây bệnh. Kết quả(:) Vi khuẩn gram âm chiếm đa số (81,43%) hơn so với vi khuẩn gram dương (18,57%). Thường gặp nhất là K. pneumonia (25,7%), A. baumannii (21,43%), P. aeruginosae (17,14%). Các Vi khuẩn gram dương chiếm tỉ lệ thấp hơn (18,57%), với S. pneumonia (4,3%), Staphylococcus spp. (14,3%). S. pneumonia đề kháng cao với Penicillin và Macrolide. Staphylococcus spp. chỉ không đề kháng với Linesolide. P. aeruginosa chỉ còn đề kháng tương đối thấp với Imipenem, meropenem, Amikacin. K.pneumoniae đề kháng tương đối thấp với Amikacin. A. baumannii kháng cao với tất cả kháng sinh, chỉ còn kháng thấp với Cefoperazol/sulbactam (20%). Kết luận(:) Vi khuẩn gram âm chiếm đa số so với vi khuẩn gram dương. Các chủng vi khuẩn thường gặp là K. pneumonia, A. baumannii, P. aeruginosae, Staphylococcus spp. Các vi khuẩn gây đợt kịch phát COPD rất đa dạng và gia tăng đề kháng kháng sinh.

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