Đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị hội chứng thận hư tiên phát trẻ em tại Bệnh viện Sản nhi Bắc Giang

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Thị Huệ Đoàn, Bích Hoàng Nguyễn, Văn Sang Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại: 618.9 Pediatrics and geriatrics

Thông tin xuất bản: Khoa học và Công nghệ - Đại học Thái Nguyên, 2018

Mô tả vật lý: 45547

Bộ sưu tập: Metadata

ID: 492301

Thêm vào giỏ

Describe the characteristics of clinical manifestations, laboratory findings in children with idiopathic nephrotic syndrome at Bac Giang hospital for women and children. Method: Prospective study and case series. From February 2017 to May 2018. Results: Forty six children with idiopathic nephrotic syndrome (INS) were recruited into the study. The mean age at the first presentation was 6.5 years old. 69.5% of them were under 8 years old. Males got involved in NS more than females with the ratio male to female of 5.75:1. The percentages of severe edema, hypertension, microscopic hematuria and oliguria were 34.8%, 10.8%, 15.2% respectively, hypoproteinemia, hypoalbuminemia, hypercholesterolemia and mass proteinuria (158.3 mg/kg/day). Corticosteroid sensitive NS was 89.7%. The mean time of steroid response was 11.3 days. Conclusions: Children with idiopathic nephrotic syndrome most were under 8 years old, males, edema, hypoproteinemia, mass proteinuria. Children with NS at the first presentation are able to treat and follow-up in Bac Giang City.Mô tả đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị Hội chứng thận hư tiên phát nhập viện tại Bệnh viện Sản Nhi Bắc Giang. Phương pháp nghiên cứu: Tiến cứu và mô tả ca bệnh. Thời gian: Từ 2/2017 đến 5/2018. Kết quả: Có 46 bệnh nhi được chọn vào mẫu nghiên cứu. Nam mắc bệnh nhiều hơn nữ với tỷ lệ 5,75/1 (có 8 nữ và 38 nam). Tuổi trung bình là 6,5 tuổi (từ 16 tháng đến 15 tuổi), 69,5% trường hợp <
8 tuổi. Tỷ lệ phù mức độ nặng là 34,8%
tăng huyết áp 10,8%
đái máu vi thể 15,2%. Protein niệu 24 giờ trung bình là 158,3 mg/kg/ngày
protid máu giảm nặng, cholesterol máu tăng. Đáp ứng với corticosteroid là 89,7% với thời gian đáp ứng trung bình là 11,3 ngày. Kết luận: Bệnh nhi mắc hội chứng thận hư gặp phần lớn là trẻ nam, chủ yếu tuổi nhỏ, triệu chứng chủ yếu là phù, giảm nặng protid máu và protein niệu nhiều. Bệnh hoàn toàn có thể điều trị và theo dõi tại địa phương.

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