Object: To investigate some clinical, para-clinical characteristics of SLE treated at Departmenr of Dermato-Venereology, No.108 military central hospital from 712010 to 712015. Subject and method: 80 with SLE. A final diagnosis was confirmed by 11 standard of revised 1997 American College of Rhematology Criteria for systemic lupus erythematosus. Results: Cause was hospitalized fever 55 percent, arthritis 30 percent, erythema 28.8 percent. By 11 standard: ANA 92.5 percent, arhritis 83.3 percent, ds-DNA 82.5 percent, renal disorder 82.5 percent, malar rash: 63.3 percent, photosensitivity: 56.3 percent, hematologic disorder: 57.5 percent, senrositic: 18.7 percent, neurologic disorder: 13.8 percent, oral ulcers: 10 percent. Other symptoms: Alopecia 28.1 percent, Raynaud syndrome 11.3 percent, increased SGOT 31.2 percent and SGPT 20 percent, decreased protein 62.5 percent and albumin 77.5 percent. Conclusion: clinical SLE has diversified by skin disorder and multiorgan.