Osteoblast cell behavior on polyetheretherketone dental implant surfaces treated with different grit size aluminum oxide particles: An in vitro analysis.

• Tác giả: Amit Gaikwad, Marjan Kheirmand Parizi, Meike Stiesch, Andreas Winkel
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : The Journal of prosthetic dentistry , 2025
• Bộ sưu tập: NCBI
• ID: 495185

Tóm tắt

 STATEMENT OF PROBLEM: The hydrophobic and bioinert nature of polyetheretherketone (PEEK) implants needs to be addressed for successful osseointegration. PURPOSE: The purpose of this in vitro study was to evaluate the osteoblast cell behavior on PEEK implant surfaces treated with airborne-particle abrasion using different grit size aluminum oxide (Al MATERIAL AND METHODS: Disk-shaped specimens (n=96) were prepared from medical grade PEEK rods and were distributed into 4 groups (n=24) of untreated PEEK (PEEK 0), airborne-particle abrasion using 50-μm Al RESULTS: The lowest mean WCA was demonstrated in PEEK 150 (49.25 ±5.51) and the highest in PEEK 0 (89.14 ±4.24) (P<
 .001). SEM images of PEEK 150 illustrated a more complex structure with a large area of globular outcroppings throughout the surface. PEEK 150 showed the highest cell metabolic activity at each time point with florescence staining showing a substantial cell confluence at day 3 and 7. Although PEEK 150 did not show a significant increase in cell proliferation, the number of cells attached was significantly higher than other groups (P<
 .05). PEEK 110 and 150 also showed a substantial increase in the extent of mineralization. CONCLUSIONS: Airborne-particle abrasion using moderate Al