A-Kinase-Anchoring Protein Subtypes Differentially Regulate GPCR Signaling and Function in Human Airway Smooth Muscle.

• Tác giả: Aaron H Cohen, Deepak A Deshpande, Isabella Dewes, Arun K Jannu, Elham Javed, Ajay P Nayak, Raymond B Penn, Dale D Tang, Ruping Wang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 912.01 Philosophy and theory
• Thông tin xuất bản: United States : American journal of respiratory cell and molecular biology , 2025
• Bộ sưu tập: NCBI
• ID: 495565

Tóm tắt

AKAPs (A-kinase-anchoring proteins) act as scaffold proteins that anchor the regulatory subunits of the cAMP-dependent PKA (protein kinase A) to coordinate and compartmentalize signaling elements and signals downstream of Gs-coupled GPCRs (G protein-coupled receptors). The β