The rehabilitation of patient function and esthetics is essential from a social and psychological point of view. After a maxillary resection, the supporting structures that help provide retention or stability to a removable prosthesis are lacking. An effective, functional, straightforward, comfortable, and esthetic prosthetic rehabilitation of a patient with a resected maxilla using a digital workflow is presented. The rehabilitation was done using a computer-aided design and computer-aided manufactured bar and clip-supported overdenture prosthesis over quad zygomatic implants.