YTHDF2-mediated m

• Tác giả: Hongzhen Chen, Chunhui Cui, Xingdi Fan, Tiansu Geng, Fangyi Han, Zhien Lan, Yongwei Lin, Ke Mo, Xing Niu, Bowen Qiu, Zhilin Shu, Haocheng Wang, Junming Wu, Ziying Wu, Ziqian Xian, Yaping Ye, Zhiwei Ye, Yao Ying, Fanan Zeng, Kehong Zheng
• Ngôn ngữ: eng
• Ký hiệu phân loại: 070.48346 Journalism
• Thông tin xuất bản: Scotland : Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy , 2025
• Bộ sưu tập: NCBI
• ID: 496587

Tóm tắt

AIMS: Chemoresistance results in poor outcomes of patients with gastric cancer (GC). This study aims to identify oxaliplatin resistance-related cell subpopulations in the tumor microenvironment (TME) and decipher the involved molecular mechanisms. METHODS: Through single-cell RNA sequencing, a unique ONECUT2 RESULTS: The abundance of ONECUT2 CONCLUSIONS: Our study demonstrates that YTHDF2-mediated m