Diagnostic testing for hemophagocytic lymphohistiocytosis.

• Tác giả: Jack J Bleesing, Samuel Cern Cher Chiang, Rebecca A Marsh
• Ngôn ngữ: eng
• Ký hiệu phân loại: 155.282 Diagnostic graphology
• Thông tin xuất bản: Netherlands : Journal of immunological methods , 2025
• Bộ sưu tập: NCBI
• ID: 496925

Tóm tắt

Hemophagocytic lymphohistiocytosis (HLH) is a rare clinical syndrome caused by severe systemic hyperinflammation. HLH can be rapidly fatal if unrecognized or inadequately treated. It is important that clinicians are able to utilize diagnostic testing to assess for HLH and determine the underlying causes including possible inborn errors of immunity (IEI). This article summarizes many of the tools available to aid with the diagnostic evaluation of patients with possible HLH and underlying IEI.