Efficacy and safety of peroxide-based mouthrinse on whitening treatment: A randomized controlled clinical trial.

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Tác giả: Alessandra Bühler Borges, Karine Carvalho Dos Santos, Mariane Cintra Mailart, Carlos Rocha Gomes Torres

Ngôn ngữ: eng

Ký hiệu phân loại: 171.8 Systems based on altruism

Thông tin xuất bản: England : Journal of dentistry , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 497012

 OBJECTIVES: This randomized controlled clinical trial evaluated the efficacy and safety of peroxide-based mouthrinse on whitening treatment. The patient's satisfaction and treatment longevity were also assessed. MATERIAL AND METHODS: Participants (N = 45) were randomly allocated to three different groups: WM (Whitening mouthrinse - 2.5% hydrogen peroxide)
  PM (Placebo mouthrinse - 0% hydrogen peroxide)
  and WG (Whitening gel - 10% carbamide peroxide). The treatment was performed twice daily for 30 s over 90 days for WM and PM and once daily for 2 h over 14 days for WG. Tooth color was evaluated with shade guides (ΔSGU) and with a spectrophotometer (ΔE RESULTS: WG resulted in the highest color change over time for visual (ΔSGU) and objective (ΔE CONCLUSIONS: The peroxide-based mouthrinse effectively changed tooth color, with relevant effect detected after 60 days of use. However, the whitening result obtained with the conventional carbamide peroxide gel treatment was more pronounced. No relevant adverse effects were observed, and the outcomes were maintained for 2 years. CLINICAL SIGNIFICANCE: Peroxide-based mouthrinse is an effective alternative whitening treatment, although it promotes less color change compared with the conventional at-home technique without inducing significant adverse effects. Patients should be warned about the prolonged treatment and the need for compliance.
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