OBJECTIVE: Venous stenting has become the standard of care for patients with iliofemoral venous stenosis who have failed conservative therapy. Although outcome data following such stenting exist for Wallstents and Wallstent-Zenith (Z) stent combination, such data for dedicated stents is sparse outside of industry-sponsored trials. This study aims to address this gap by comparing the outcomes of matched cohorts of limbs that underwent stenting with either the Medtronic Abre stent (Medtronic Inc), the Bard Venovo stent (Becton, Dickinson, and Co), or Wallstent-Z stent combination (Boston Scientific
Cook Medical Inc). METHODS: Contemporaneously entered data on matched cohorts of patients who underwent stenting from 2016 to 2022 for quality of life (QoL)-impairing iliofemoral venous stenosis (not occlusion) after failing conservative therapy was analyzed. The venous clinical severity score (VCSS, 0-27), grade of swelling (GOS, 0-4), visual analog scale pain score (VAS pain score, 0-10), and CIVIQ-20 QoL scores were evaluated initially and post stenting to assess the effects of stenting. Analysis of variance and paired t-tests were used to compare clinical and QoL variables, whereas Kaplan-Meier analysis was used to examine primary, primary-assisted, and secondary stent patencies, with log-rank test used to discriminate between different curves. RESULTS: There were a total of 198 limbs that had undergone stenting, including 68 in the Abre, 60 in the Venovo and 70 in the Wallstent-Z stent groups. The median age for the entire cohort was 65 years (range, 21-101 years). The cohort included 141 women and 57 men. Left laterality (112 limbs) was more common than right laterality (86 limbs). Post-thrombotic syndrome was seen in 146 limbs and nonthrombotic iliac vein lesions/May-Thurner syndrome in 52 limbs. The median body mass index was 35 kg/m CONCLUSIONS: For patients undergoing stenting for QoL-impairing symptoms of iliofemoral venous stenosis after failing conservative therapy, Abre, Venovo, and Wallstent-Z stent combination all appear to provide similar clinical and QoL improvement. A significant difference between stent patencies for the three stent types was also not detected. Stent selection for treatment of stenotic lesions of the iliofemoral venous territory can be based on stent availability and the preference/expertise of the interventionalist.