Transcriptional dynamics of porcine granulosa cells during cellular acclimation to thermal challenge.

• Tác giả: Jaya Bharati, Salam Jayachitra Devi, Vivek Kumar Gupta, Satish Kumar, N H Mohan
• Ngôn ngữ: eng
• Ký hiệu phân loại: 785.13 *Trios
• Thông tin xuất bản: England : Journal of thermal biology , 2025
• Bộ sưu tập: NCBI
• ID: 497748

Tóm tắt

Investigations on heat stress induced transcriptomic changes is critical to characterization of candidate genes for thermal adaptability in livestock. Continues spells of high ambient temperature due to climate change has amplified reproductive dysfunctions, necessitating immediate attention. The present study aimed to explore the transcriptomic signature of heat stressed granulosa cells (GCs) and signalling pathways regulating their adaptability to thermal challenge. The GCs were collected from small follicles (3-6 mm) of pig ovary. The GCs primary culture was subjected to in vitro heat stress challenge at 42