INTRODUCTION & OBJECTIVES: There is limited evidence regarding sexual satisfaction among female partners of patients with penile prosthesis (PP) and factors influencing it. MATERIALS & METHODS: Single-center, retrospective, observational study including all patients aged ≥18 years who underwent PP implantation (inflatable and malleable types) between October 2007-December 2022 at Hospital 12 de Octubre, Madrid, Spain. 73 female partners completed the Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) questionnaire (5-item partner version). Each question was scored from 0 (lowest satisfaction) to 4 (highest satisfaction), resulting in an overall EDITS score ranging from 0 to 100. Variables collected: time since surgery, monthly intercourse frequency, type and brand of PP, initial placement rationale, new versus replacement surgery, total and inflatable PP part length. RESULTS: Average (standard deviation) scores were: 3.3 (0.9), 3.19 (0.9), 2.42 (0.8), 3.45 (0.9), and 3.67 (0.8). The overall average satisfaction score was 80 (12.4). Statistical analysis revealed no significant correlations between female partners' satisfaction and their age (r = -0.128), actual age of the patient (r = -0.041), time since surgery (r = -0.072), monthly intercourse frequency (r = 0.164), type of PP (p = 0.521), brand of inflatable PP (p = 0.582), causes of erectile dysfunction (p = 0.174), number of replacements (p = 0.705), total (r = 0.167) or inflatable PP part length (r = 0.134).