Nghiên cứu nồng độ ferritin huyết thanh ở bệnh nhân rối loạn lipid máu

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Tác giả: Ngọc Minh Châu Bùi, Ngọc Tú Đoàn, Nguyên Trang Nguyễn, Hữu Dàng Trần, Thị Quỳnh Quyên Trần

Ngôn ngữ: vie

Ký hiệu phân loại: 616.970654 Other diseases

Thông tin xuất bản: Tạp chí Nội tiết và Đái tháo đường, 2021

Mô tả vật lý: 90-98

Bộ sưu tập: Metadata

ID: 498617

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Dyslipidemia is one of the public health problems and the main cardiovascular risk factors. The study was conducted to determine serum ferritin concentration, ferritin increase rate in serum and evaluate the relationship between serum ferritin concentration with bilan lipid components. Methods: Cross-sectional descriptive study with a controlled comparison in 156 patients at the Department of General Internal Medicine - Geriatrics, collected cardiovascular risk factors caused by atherosclerosis and diabetes mellitus, biland lipid blood and blood ferritin test. Results: The mean ferritin concentration in dyslipidemia group was 544.21 ± 351.28 ng/ml, higher than the control group (118.56 ± 64.58 ng/ml)
There was a significant difference in the rate of increase of serum ferritin, average concentration of ferritin between the two groups dyslipidemia and the control group (p <
0.001)
The rate of increase of serum ferritin in the dyslipidemia group was 100%
Rate of serum ferritin increase in people with increased LDL-C is 100%, in people with reduced HDL-C is 100%, in people with increased TG is 100%, in people with TC increase is 100%. The average ferritin concentration in the subjects with dyslipidemia with 2 elements (Increased LDL-C, TG) and 3 elements (Increased LDL-C, TG, TC) is the highest with mean value and standard deviation, is: 654.67 ± 479.98 ng/ml. Conclusions: There is a close relationship between ferritin concentration and dyslipidemiaRối loạn lipid máu (RLLM) là một trong những vấn đề sức khỏe cộng đồng trên thế giới và là một trong những yếu tố nguy cơ tim mạch chính. Đề tài được tiến hành nhằm xác định nồng độ ferritin huyết thanh, tỷ lệ tăng ferritin huyết thanh và đánh giá mối liên quan giữa nồng độ ferritin huyết thanh với các thành tố của bilan lipid. Đối tượng và phương pháp nghiên cứu: nghiên cứu mô tả cắt ngang có so sánh đối chứng ở 156 bệnh nhân tại khoa Nội tổng hợp - Lão khoa. Bệnh nhân được thu thập các dữ liệu: yếu tố nguy cơ bệnh tim mạch do xơ vữa và đái tháo đường và làm xét nghiệm biland lipid máu, xét nghiệm Feritin máu. Kết quả: Nồng độ trung bình của ferritin ở đối tượng có RLLM cả 2 giới là 544,21 ± 351,28 ng/ml cao hơn nồng độ trung bình ferritin của nhóm chứng là 118,56 ± 64,58 ng/ml. Có sự khác biệt có ý nghĩa thống kê về tỉ lệ tăng ferritin huyết thanh, nồng độ trung bình ferritin chung giữa 2 nhóm RLLM và nhóm chứng (p <
0,001). Tỉ lệ tăng ferritin huyết thanh ở nhóm RLLM là 100%, Tỉ lệ tăng ferritin huyết thanh: ở người tăng LDL-C là 100%, ở người giảm HDL-C là 100%, ở người tăng TG là 100%, ở người tăng TC là 100%. Nồng độ trung bình của ferritin ở đối tượng có RLLM có 2 thành tố (Tăng LDL-C, TG) và 3 thành tố (Tăng LDL-C, TG, TC) là cao nhất có giá trị trung bình và độ lệch chuẩn lần lượt là: 654,67 ± 479,98 ng/ml. Kết luận: Có mối liên quan chặt chẽ giữa nồng độ ferritin và RLLM.

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