Vai trò của thang điểm SARC-F trong dự đoán nguy cơ tiến triển ở bệnh nhân Covid-19 cao tuổi điều trị tại Bệnh viện Dã chiến Truyền nhiễm 5G

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Duy Đông Nguyễn, Ngọc Khánh Nguyễn, Thị Dịu Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại: 362.1962414 Physical illness

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2022

Mô tả vật lý: 158-163

Bộ sưu tập: Metadata

ID: 498699

Thêm vào giỏ

Tóm tắt
Chủ đề

Điều tra mối liên quan giữa nguy cơ suy nhược cơ và độ nặng của bệnh ở bệnh nhân COVID-19 cao tuổi. Phương pháp: Một nghiên cứu thuần tập tiến cứu trên 182 bệnh nhân lớn tuổi nhập viện (≥60 tuổi) bị viêm phổi do COVID-19 được xác nhận trong khoảng thời gian từ ngày 6 tháng 9 năm 2021 đến ngày 30 tháng 10 năm 2021. Dữ liệu dịch tễ học, nhân khẩu học xã hội, lâm sàng và xét nghiệm lúc nhập viện và dữ liệu kết quả được trích xuất từ hồ sơ bệnh án điện tử. Tất cả các bệnh nhân được đánh giá về tình trạng suy nhược cơ khi nhập viện bằng thang điểm SARC-F và kết quả là sự phát triển của bệnh nặng hơn trong thời gian nằm viện. Chúng tôi đã sử dụng mô hình nguy cơ theo tỷ lệ Cox để xác định mối liên quan giữa suy nhược cơ và sự tiến triển của bệnh. Kết quả: Trong số 182 bệnh nhân, 87 (47,8%) bệnh nhân có nguy cơ cao mắc suy nhược cơ trong khi 95 (52,2%) thì không. 42 (23,1%) bệnh nhân tiến triển thành các trường hợp nặng hơn. Bệnh nhân COVID-19 có nguy cơ mắc suy nhược cơ cao hơn có nhiều khả năng phát triển bệnh nặng hơn những người không mắc bệnh (36,8% so với 10,5%, p <
0,001). Sau khi điều chỉnh các yếu tố nhân khẩu học, lâm sàng, và xét nghiệm, nguy cơ suy nhược cơ cao hơn có liên quan đến nguy cơ tình trạng nặng cao hơn [tỷ lệ nguy cơ = 6,37 (KTC 95%: 1,61-25,18)]. Kết luận: Nguy cơ suy nhược cơ ở bệnh nhân cao tuổi mắc COVID-19 là phổ biến. Những người có nguy cơ suy nhược cơ cao hơn có nhiều khả năng phát triển tình trạng nghiêm trọng hơn. Một đánh giá đơn giản với bác sĩ về tình trạng suy nhược cơ có thể giúp cảnh báo sớm những bệnh nhân lớn tuổi có nguy cơ cao bị viêm phổi COVID-19 nặng.To investigate the association between the risk of myasthenia gravis and disease severity in elderly COVID-19 patients. Methods: A prospective cohort study of 182 hospitalized elderly patients (≥60 years of age) with confirmed COVID-19 pneumonia between September 6, 2021 and October 30, 2021. Epidemiological, sociodemographic, clinical and laboratory data on admission and outcome data were extracted from electronic medical records. All patients were assessed for myasthenia gravis on admission using the SARC-F score and as a result the development of worsening disease during hospital stay. We used the Cox proportional hazard model to determine the association between sarcopenia and disease progression. Results: Among 182 patients, 87 (47.8%) were at high risk for sarcopenia while 95 (52.2%) were not. We found that 42 (23.1%) patients progressed to more severe cases. COVID-19 patients at higher risk of developing sarcopenia were more likely to develop severe disease than those without (36.8% vs 10.5%, p <
0.001). After adjusting for demographic and clinical, and laboratory factors, a higher risk of sarcopenia was associated with a higher risk of severe condition [hazard ratio =6.37 (95% CI: 1,61-25,18)]. Conclusion: The risk of sarcopenia in elderly patients with COVID-19 was common. People with at higher risk of sarcopenia were more likely to develop more serious conditions. A simple physician assessment of sarcopenia can provide early warning in older patients who are at high risk for more severe COVID-19 pneumonia.

Tạo bộ sưu tập với mã QR