Bước đầu đánh giá hiệu quả sử dụng huyết tương giàu tiểu cầu tự thân ở các bệnh nhân có tiên lượng khó trong thụ tinh trong ống nghiệm

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Thị Mai Lương Đặng, Thùy Hương Đỗ, Tiến Tùng Dương, Ngọc Dung Lê, Mạnh Hà Nguyễn, Phúc Hoàn Nguyễn, Thanh Hoa Nguyễn, Thị Minh Khai Nguyễn, Thị Ngọc Yến Trịnh

Ngôn ngữ: vie

Ký hiệu phân loại: 581.3 +Genetics and evolution

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2022

Mô tả vật lý: 34-38

Bộ sưu tập: Metadata

ID: 499029

Thêm vào giỏ

Tóm tắt
Chủ đề

A clinical trial study to evaluate the effectiveness of autologous platelet-rich therapy intrauterine infusion in patients with thin endometrium (TE) and patients with repeated implantation failure (RIF) in IVF. Results: in TE group, the thickness of the endometrium after PRP infusion increased significantly compared to before (5,8 ± 1.01 mm vs. 6,73 ± 0,72 mm, p=0,002). The pregnancy rate (PR), clinical pregnantcy rate (CPR) and ongoing pregnancy rate (OPR) in TE group were 54,5%
54,5% and 45,5%, respectively. In RIF group, the PR, CPR, OPR were 23,08%
23,08% and 7,7%
respectively. Conclusions: Intrauterine autologous PRP infusion improved significantly the endometrial thickness and successful rate in IVF in some patients with thin endometrium. No improvement in pregnancy rate was observed in RIF group used PRP therapyNghiên cứu thử nghiệm lâm sàng nhằm đánh giá hiệu quả phối hợp điều trị của liệu pháp bơm huyết tương giàu tiểu cầu tự thân (PRP) vào buồng tử cung trên bệnh nhân có niêm mạc tử cung (NMTC) mỏng và bệnh nhân thất bại làm tổ liên tiếp (TBLTLT) trong thụ tinh trong ống nghiệm. Kết quả: ở nhóm NMTC mỏng, độ dày NMTC sau bơm PRP tăng rõ rệt so với trước bơm (5,8 ± 1.01 mm so với 6,73 ± 0,72 mm, p=0,002). Tỷ lệ có thai, tỷ lệ thai lâm sàng, thai diễn tiến ở nhóm NMTC mỏng có điều trị liệu pháp bơm PRP tự thân tương ứng là 54,5%
54,5% và 45,5%. Tỷ lệ có thai, tỷ lệ thai lâm sàng, tỷ lệ thai diễn tiến ở nhóm TBLTLT có điều trị liệu pháp PRP tự thân tương ứng là 23,08%
23,08% và 7,7%. Kết luận: Liệu pháp bơm PRP tự thân vào buồng tử cung giúp cải thiện rõ rệt độ dày NMTC, cải thiện tỷ lệ có thai ở một số BN có NMTC mỏng. Chưa thấy có sự cải thiện về tỷ lệ có thai ở nhóm TBLTLT được sử dụng liệu pháp bơm PRP.

Tạo bộ sưu tập với mã QR