Một số yếu tố liên quan với mất cơ ở bệnh nhân loãng xương cao tuổi

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Tác giả: Ngọc Tâm Nguyễn, Trung Anh Nguyễn, Thị Thanh Huyền Vũ

Ngôn ngữ: vie

Ký hiệu phân loại: 612.744 Biochemistry

Thông tin xuất bản: Tạp chí Y dược lâm sàng 108, 2022

Mô tả vật lý: 57-62

Bộ sưu tập: Metadata

ID: 499242

Thêm vào giỏ

To assess some factors related to sarcopenia among older osteoporosis patients. Subject and method: A cross-sectional study was conducted in National Geriatrics Hospital. Sarcopenia was defined by using AWGS 2019 criteria. Some related factors with sarcopenia were general characteristics, calcinemia, Vitamin D, lipid disorders, geriatric characteristics including frailty, disabilities and physical activity. Result: A total of 143 osteoporosis older patients was recruited in the study (mean age 72.8 ± 8.7 years). BMI was significantly associated with sarcopenia in study population (p<
0.001). The rate of severe sarcopenia was significantly lower in lacking vitamin D group (33%) than in normal group (12%). Conclusion: Some factors associated with sarcopenia in older osteoporosis patients were age, BMI and vitamin D. Early screening stratergy for sarcopenia among those patients was neccesary.Xác định một số yếu tố liên quan tới mất cơ ở bệnh nhân cao tuổi có loãng xương. Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang được thực hiện tại Bệnh viện Lão khoa Trung ương. Mất cơ được chẩn đoán theo tiêu chuẩn châu Á AWGS năm 2019. Các yếu tố liên quan tới mất cơ được nghiên cứu bao gồm đặc điểm chung, chỉ số sinh hoá máu như calci, vitamin D và lipid máu, các đặc điểm lão khoa như hội chứng dễ bị tổn thương, suy giảm chức năng hoạt động hàng ngày, mức độ hoạt động thể lực. Kết quả: Nghiên cứu được thực hiện trên 143 đối tượng người bệnh nhân loãng xương cao tuổi(tuổi trung bình 72,8 ± 8,7 năm). Có mối liên quan giữa BMI và tình trạng mất cơ ở bệnh nhân loãng xương (p<
0,001). Tỷ lệ mất cơ nặng thấp hơn có ý nghĩa thống kê ở nhóm không thiếu (12%) so với nhóm thiếu vitamin D(33%). Không có mối liên quan có ý nghĩa thống kê giữa một số đặc điểm lão khoa như hội chứng dễ bị tổn thương và suy giảm chức năng hàng ngày với mất cơ ở bệnh nhân cao tuổi bị loãng xương. Kết luận: Trên bệnh nhân cao tuổi mắc loãng xương, tuổi cao trên 80, BMI thấp và nồng độ vitamin D thấp có liên quan tới gia tăng tỷ lệ mắc mất cơ. Cần có chiến lược sàng lọc sớm mất cơ cho những đối tượng này.

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