Đánh giá hiệu quả chạy thận nhân tạo thông qua Kt/V trên bệnh nhân chạy thận nhân tạo định kỳ tại Khoa Thận nhân tạo, Bệnh viện Chợ Rẫy

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Thị Ngọc Ánh Đoàn, Minh Trí Hồ, Quốc Trúc Hồ, Thị Tuyết Vân Huỳnh, Hồng Thanh Trúc Ngô, Minh Tuấn Nguyễn, Thị Kiều Diễm Nguyễn, Trần Đức Nguyễn, Văn Xuân Nguyễn, Văn Hiền Phạm, Quốc Duy Cương Trần, Thị Thanh Vân Trương, Thị Hồng Yến Võ, Thị Thanh Lan Võ

Ngôn ngữ: vie

Ký hiệu phân loại: 544.5 Qualitative analysis

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2022

Mô tả vật lý: 329-334

Bộ sưu tập: Metadata

ID: 500492

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Chủ đề

Đánh giá hiệu quả sự thanh thải của urê trong chạy thận nhân tạo (CTNT) bằng chỉ số spKt/V là cần thiết trong điều trị bệnh nhân mắc bệnh thận mạn giai đoạn cuối (BTMGĐC), với nhiều phương pháp đánh giá sẽ giúp nhà chuyên môn lựa chọn phương án tối ưu nhất trong điều trị bệnh lý này. Nghiên cứu được thực hiện nhằm đánh giá hiệu quả CTNT bằng cách so sánh chỉ số spKt/V ở phương pháp đo trực tiếp trên máy và phương pháp tính toán theo công thức Daugridas. Nghiên cứu mô tả cắt ngang được thực hiện trên 175 bệnh nhân mắc BTMGĐC đang lọc máu tại bệnh viện Chợ Rẫy từ tháng 1-6/2022, chỉ số spKt/V được đo bằng hai phương pháp trên và tính giá trị trung bình, sử dụng kiểm định Willcoxon signrank để so sánh 2 giá trị đó. Kết quả cho thấy chỉ số trung bình spKt/V ở phương pháp đo trực tiếp trên máy (1,77 (1,5 - 2,06)) và phương pháp tính toán bằng công thức Daugridas (1,6 (1,36 - 1,82)) đều nằm trong giá trị được khuyến cáo. Kiểm định Willcoxon signrank cho thấy sự khác biệt chỉ số spKt/V ở hai phương pháp có ý nghĩa thống kê và Mô hình hồi quy tuyến tính cho thấy có sự tương quan chặt chẽ với hệ số tương quan R = 0,65 và R2 = 0,423 (p<
0,001). Vì vậy, nhà chuyên môn cần cân nhắc nên lựa chọn phương pháp đo trực tiếp trên máy để đánh giá và điều chỉnh các thông số trong quá trình CTNT để giúp cho bệnh nhân điều trị hiệu quả bệnh lý mắc phải này.Evaluating the effectiveness of urea clearance in hemodialysis by the spKt/V indicator is necessary for treating patients with end-stage chronic kidney disease (ESRD). Multiple evaluation methods could support the specialists in choosing the best treatment methods for this disease. This study was conducted to evaluate the effectiveness of hemodialysis by comparing the spKt/V indicator in direct measurement on the machine to the calculation method according to the Daugridas formula. The cross-sectional descriptive study on 175 patients with ESRD undergoing hemodialysis at Cho Ray Hospital from January to June 2022 used the Willcoxon Signrank Test to compare the average spKt/V calculated by the two methods above. The results show that the average spKt/V calculated by the direct measurement on the machine (1.77 (1.5-2.06)) and the Daugridas formula (1.6 (1.36)-1.82)) were all within the recommended value. The Willcoxon Signrank Test illustrates a statistically significant difference in spKt/V in the two methods, while the Linear regression model shows a strong correlation with correlation coefficients R = 0.65 and R2 = 0.423 (p<
0.001). Therefore, experts need to consider choosing an optimal method of measuring directly on the machine to evaluate and adjust parameters during the hemodialysis process in their professional interest to effectively treat the disease.

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