Đặc điểm xét nghiệm huyết học và tình trạng tăng đông ở bệnh nhân covid 19 tại trung tâm hồi sức tích cực Long An năm 2021

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Tác giả: Thị Hương Lan Lê, Thị Minh Thiện Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại: 362.1962414 Physical illness

Thông tin xuất bản: Tạp chí Khoa học và Công nghệ Đại học Thái Nguyên, 2022

Mô tả vật lý: 157-164

Bộ sưu tập: Metadata

ID: 500717

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Chủ đề

Nghiên cứu đặc điểm một số tế bào máu ngoại vi và tình trạng tăng đông ở bệnh nhân COVID -19 điều trị tại tung tâm hồi sức tích cực tỉnh Long An. Đối tượng gồm 187 bệnh nhân, sử phương pháp nghiên cứu mô tả cắt ngang. Kết quả cho thấy tỷ lệ thiếu máu ở bệnh nhân nghiên cứu là 25,4% ở nam và 39,2% ở nữ. Giá trị trung bình bạch cầu là 11,28 ± 5,66 G/L. Bệnh nhân COVID-19 có tăng bạch cầu trung tính, monocyte với tỷ lệ lần lượt là 55,1% và 39,6%
bạch cầu lympho giảm chiếm tỷ lệ 74,3%., Giá trị trung bình tiểu cầu là 278,66 ± 115,3 G/L và gặp 8,0% bệnh nhân giảm số lượng tiểu cầu. Giá trị trung bình Fibrinogen là 5,15 ± 1,62 g/L., Nồng độ D-dimer trung bình là 4,81 ± 12,99 mg/L, các chỉ số đông máu cơ bản PT, APTT có biến đổi nhưng không đáng kể. Có mối liên quan giữa 2 chỉ số Fibronogen và D-dimer với hệ số tương quan r=-0,22. Một số chỉ số tế bào máu ngoại vi ở bệnh nhân COVID-19 có sự thay đổi theo diễn tiến bệnh, biểu hiện thiếu máu, tăng bạch cầu trung tính và monocyte, giảm bạch cầu lympho và tiểu cầu. Bệnh nhân COVID-19 thường có Fibrinogen và D-dimer tăng, biểu hiện tình trạng tăng đông ở bệnh nhân COVID-19 theo mức độ bệnh.The research studies on characteristics of some peripheral blood cells and hypercoagulability in COVID-19 patients treated at the intensive care center in Long An province. Subjects included 187 patients, using a descriptive cross-sectional study method. The results showed that the rate of anemia in the study patients was 25.4% in men and 39.2% in women. The mean value of white blood cell was 11.28 ± 5.66 G/L., Patients with COVID-19 have increase neutrophil, monocytosis with the rates of 55.1% and 39.6% respectively
decrease lymphocyte with rates 74.3%. Platelets mean values were 278.66 ± 115.3 G/L and 8.0% of patients has an decreased in platelets counts. Fibrinogen mean values was 5.15 ± 1.62 g/L. D-dimer mean values was 4.81 ± 12.99 mg/L. There was a week corelation between Fibrinogen and D-dimer (r=-0.22). Patients with COVID-19 have anemia, increase netrophill and monocyst, decrease lymphocyte and platelets counts. Patients with COVID-19 often have elevated fibrinogen and D-dimer, presenting as hypercoagulability in COVID-19 patients according to the severity of the disease.

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