Mối liên quan giữa chỉ số bạch cầu đoạn trung tính trên bạch cầu lympho và chỉ số tiểu cầu trên bạch cầu lympho máu ngoại vi với một số đặc điểm bệnh nhân bệnh thận mạn tính giai đoạn cuối

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Tác giả: Việt Thắng Lê, Trung Kiên Nguyễn, Việt Hưng Tạ

Ngôn ngữ: vie

Ký hiệu phân loại: 612.12 Blood chemistry

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2022

Mô tả vật lý: 566-571

Bộ sưu tập: Metadata

ID: 500747

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Evaluation the relationship between neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) with some characteristics of patients with end-stage chronic kidney disease. Subjects and methods: A crosssectional study was conducted on 101 end-stage chronic kidney disease patients who treated at Nephrology and Hemodialysis Department, Military Hospital 103 from March 2020 to June 2021. Results: The group of patients older than 40 years old had a significantly higher median value of NLR than the group of patients under 40 years old. Meanwhile, the median value of PLR in the group of patients with increased Procalcitonin (PCT) was significantly higher than in the group of patients without increased PCT. The median values of NLR and PLR in the group of patients with increased C-Reactive protein (CRP) were statistically significantly higher than in the group of patients without increased CRP. The group of patients with elevated CRP had a 4.593 times higher of increase NLR rate than the group of patients without elevated CRP (p <
0.01). Conclusion: Median values of NLR and PLR indices in the group of chronic kidney disease patients are associated with age, elevated CRP and PCT concentration.Khảo sát mối liên quan giữa chỉ số bạch cầu đoạn trung tính trên bạch cầu lympho (NLR) và chỉ số tiểu cầu trên bạch cầu lympho (PLR) với một số đặc điểm bệnh nhân bệnh thận mạn tính giai đoạn cuối. Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang trên 101 bệnh nhân bệnh thận mạn tính giai đoạn cuối điều trị tại khoa Thận - Lọc máu, Bệnh viện quân y 103 từ tháng 03/2020 đến tháng 06/2021. Kết quả: Nhóm bệnh nhân trên 40 tuổi có giá trị trung vị chỉ số NLR cao hơn có ý nghĩa so với nhóm bệnh nhân dưới 40 tuổi. Trong khi đó, giá trị trung vị chỉ số PLR ở nhóm bệnh nhân có tăng Procalcitonin (PCT) cao hơn có ý nghĩa thống kê so với nhóm bệnh nhân không tăng PCT. Giá trị trung vị chỉ số NLR và PLR ở nhóm bệnh nhân có tăng CRP cao hơn có ý nghĩa thống kê so với nhóm bệnh nhân không có tăng protein phản ứng C (CRP). Nhóm bệnh nhân có tăng CRP có tỷ lệ tăng NLR cao gấp 4,593 lần nhóm bệnh nhân không tăng CRP (p <
0,01). Kết luận: Giá trị trung vị của chỉ số NLR và PLR ở nhóm bệnh nhân bệnh thận mạn tính có liên quan với tuổi cao, tình trạng tăng CRP và PCT huyết tương.

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