Đặc điểm của chỉ số bạch cầu hạt chưa trưởng thành (Ig) trên công thức máu ở trẻ bạch cầu cấp tại Bệnh viện Nhi đồng 1

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Trần Thu Cúc Cao, Hoàng Cúc Đỗ, Thị Xuân Khánh Lương, Minh Tuấn Nguyễn, Thuỳ Dương Nguyễn, Nguyễn Liên Anh Phan, Đức Hưng Trần

Ngôn ngữ: vie

Ký hiệu phân loại: 612.12 Blood chemistry

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2022

Mô tả vật lý: 609-614

Bộ sưu tập: Metadata

ID: 500749

Thêm vào giỏ

Illustrate characteristics of Immature Granulocyte (IG) value in complete blood count of leukemia at Children's Hospital 1. Methods: Cross section study of 130 children who were diagnosed of leukemia at Children's Hospital 1 from 1/2019 to 7/2021. Results: Decrease of at least two blood cell lineages was recorded in more than 94% of cases. Abnormal cell, such as CA, LA, normoblast ..., was seen on complete blood count in around 58,5% of cases. It was shown that IG was elevated in around 50% of cases. Especially, 100% of cases was recorded at least one of three abnormal manifestations: at least two blood cell lineages were decreased, abnormal cells were noted, and value of IG was increased. All cases which reported abnormal white blood cells in IG were not diagnosed of AML. Conclusions: Increased IG is a suggestive marker for medical conditions such as infection, inflammation, or cancer, such as acute leukemia... It was pointed out that 100% of cases was recorded at least one of three abnormal manifestations: at least two blood cell lineages were decreased, abnormal cells were noted, and value of IG was increased. However, this indicator has not really been noticed in clinical practice. As a result, it is necessary to pay more attention to the IG value on complete blood count, in order to improve prognosis of leukemiaMô tả một số đặc điểm của chỉ số bạch cầu hạt chưa trường thành (IG) trên công thức máu của bệnh nhân bạch cầu cấp tại bệnh viện Nhi Đồng 1. Đối tượng và Phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang 130 trẻ được chẩn đoán bạch cầu cấp tại bệnh viện Nhi Đồng 1 từ 1/2019 - 7/2021. Kết quả: Hơn 94% trường hợp giảm ít nhất 2 dòng tế bào máu trên công thức máu. Có 58,5% trường hợp ghi nhận tế bào báo động trong công thức máu, gồm các tế bào như Atypical Cells (CA), Atypical Lymphocytes (LA), hồng cầu nhân... Gần 50% trường hợp tăng tế bào bạch cầu hạt chưa trưởng thành (IG). Đặc biệt, 100% trường hợp đều ghi nhận ít nhất 1 trong 3 dấu hiệu bất thường sau: giảm ít nhất 2 dòng tế bào máu, ghi nhận tế bào báo động, và tăng bất thường chỉ số IG. Tất cả trường hợp ghi nhận tế bào bạch cầu báo động thuộc IG (n=12) đều không phải là AML. Kết luận: Tăng IG là một dấu chỉ gợi ý cho những tình trạng bệnh lý như nhiễm trùng, viêm hay bệnh lý ung thư như bạch cầu cấp... Nghiên cứu chỉ ra rằng, 100% trường hợp BCC đều ghi nhận ít nhất 1 trong 3 dấu hiệu bất thường sau: giảm ít nhất 2 dòng tế bào máu, ghi nhận tế bào báo động, và tăng bất thường chỉ số IG. Tuy vậy, chỉ số này vẫn chưa thực sự được chú ý trên thực hành lâm sàng. Vì vậy, cần chú ý hơn chỉ số IG trên công thức máu, tránh bỏ sót, nhằm chẩn đoán sớm hơn và cải thiện tiên lượng điều trị bạch cầu cấp.

1. Đọc trực tuyến

1. Đọc trực tuyến

Tạo bộ sưu tập với mã QR