Đánh giá chất lượng cuộc sống của bệnh nhân bạch cầu mạn dòng tủy giai đoạn mạn điều trị bằng Imatinib mesylate đạt đáp ứng di truyền tế bào hoàn toàn bằng bảng câu hỏi SF-36

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Hồng Anh Châu, Nguyễn Phương Dung Cồ, Dương Thảo Quyên Nguyễn, Thị Mỹ Hòa Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại: 636.80895 Cats

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2022

Mô tả vật lý: 477-478

Bộ sưu tập: Metadata

ID: 500812

Thêm vào giỏ

Assessment of the quality of life by the SF-36 questionnaire in patients with chronic myeloid leukemia in chronic phase after treatment with Imatinib Mesylate achieved complete cytogenetic response. Subjects: Patients were diagnosed with chronic myeloid leukemia in chronic phase with BCR-ABL1 fusion gene and/or Philadelphia chromosome-positive were being treated with Imatinib mesylate achieved complete cytogenetic response in Blood Transfusion and Hematology Hospital, Ho Chi Minh City. Method: Cross-sectional study. Results: The total number of patients in the study was 261. The median age of the research population at the present time: 47 years old (16 years old - 80 years old). The male to female ratio is about 1,23:1. The mean physical health score: 74.4 ± 20.8. The mean mental health score: 75.5 ± 20.1. Factors affecting the physical and mental health: The higher the age, the lower the physical health score (p = 0.02)
the higher the severity of anemia, the lower the physical health score (p = 0.017)
patients with eyelid and facial edema and nausea had low mental health score (p = 0.004 - p = 0.002)
patients with comorbidities had low physical and mental health score (p = 0.003 - p = 0.023)
patients with musculoskeletal pain had low physical and mental health score (p = 0.008 - p = 0.014). Conclusion: Patients were diagnosed with chronic myeloid leukemia in chronic phase after treatment with imatinib mesylate achieved complete cytogenetic response and had the quality of life at an medium-good level in the physical and good level in the mental aspect.Đánh giá chất lượng cuộc sống của bệnh nhân bạch cầu mạn dòng tủy giai đoạn mạn điều trị bằng Imatinib Mesylate đạt đáp ứng di truyền tế bào hoàn toàn bằng bảng câu hỏi SF-36. Đối tượng: Tất cả các bệnh nhân được chẩn đoán xác định bạch cầu mạn dòng tủy giai đoạn mạn có đột biến gen BCR-ABL1 và/hoặc nhiễm sắc thể Philadelphia dương tính đang điều trị Imatinib Mesylate đạt đáp ứng di truyền tế bào hoàn toàn tại bệnh viện Truyền máu Huyết học TP. Hồ Chí Minh. Phương pháp nghiên cứu: Nghiên cứu cắt ngang. Kết quả: Tổng số bệnh nhân trong nghiên cứu là 261. Tuổi trung vị tại thời điểm hiện tại của dân số nghiên cứu: 47 tuổi (16 tuổi - 80 tuổi). Tỉ lệ nam:nữ là 1,23:1. Điểm trung bình sức khỏe thể chất (SKTC): 74,4 ± 20,8. Điểm trung bình sức khỏe tinh thần (SKTT): 75,5 ± 20,1. Các yếu tố ảnh hưởng SKTC và SKTT: Tuổi càng cao, điểm SKTC càng thấp (p = 0,02)
mức độ thiếu máu càng nặng, điểm SKTC càng thấp (p = 0,017)
bệnh nhân có phù mi phù mặt và buồn nôn thì điểm SKTT thấp (p = 0,004 - p = 0,002)
bệnh nhân có bệnh lý kèm theo có điểm SKTC và SKTT thấp (p = 0,003 - p = 0,023)
bệnh nhân có đau nhức cơ xương có điểm SKTC và SKTT thấp (p = 0,008 - p = 0,014). Kết luận: Bệnh nhân Bạch cầu mạn dòng tủy giai đoạn mạn điều trị Imatinib Mesylate đạt đáp ứng di truyền tế bào hoàn toàn có chất lượng cuộc sống ở mức trung bình khá ở khía cạnh thể chất và ở mức khá, tốt ở khía cạnh tinh thần.

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