Các yếu tố nguy cơ dẫn đến thất bại điều trị ở bệnh nhân viêm phổi bệnh viện do tụ cầu kháng methicillin

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Vũ Thông Đặng, Thị Thanh Vân Dương, Quốc Dũng Lâm, Phương Mai Lê, Thượng Vũ Lê, Quang Bình Trương, Thiên Phú Trương

Ngôn ngữ: vie

Ký hiệu phân loại: 362.196241 Physical illness

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2023

Mô tả vật lý: 120-124

Bộ sưu tập: Metadata

ID: 502519

Thêm vào giỏ

To determine the risk factors leading to treatment failure of nosocomial pneumonia (NP) due to methicillin-resistant Staphylococcus spp.. Methods: We conducted a prospective, cross-sectional descriptive study with 207 patients with NP due to methicillin-resistant Staphylococcus spp. infection who were treated at the Pulmonary department of Cho Ray Hospital from March 2021 to March 2023. Results: We collected 92 patients who definitely diagnosed with methicillin-resistant Staphylococcal nosocomial pneumonia. Among them, had 54 (58.7%) successful treatment, 38 (41.3%) unsuccessful treatment. There was a significant difference between the unsuccessful treatment group and the successful treatment group in the following factors: mean age (64,3 ± 12,4 vs 58,3 ± 18,3), severe NP (94.7% vs 74.1%), respiratory failure (94.7% vs 72.2%), sepsis (86.8% vs 33.3%), septic shock (76.3% vs 14.8%), mechanical ventilation (97.4% vs 25.9%), dialysis (50% vs 13%)
with p <
0.05. Conclusion: NP due to methicillin-resistant Staphylococcus spp. infection is associated with a high rate of treatment failure, and it is crucial to assess risk factors for treatment failure to treat and predict patients proactively.Xác định các yếu tố nguy cơ dẫn đến thất bại điều trị viêm phổi bệnh viện (VPBV) do tụ cầu kháng methicillin. Đối tượng và phương pháp nghiên cứu: Chúng tôi thực hiện nghiên cứu mô tả cắt ngang tiến cứu ở 207 bệnh nhân VPBV có nguy cơ nhiễm tụ cầu kháng methicillin được điều trị tại khoa Hô hấp, Bệnh viện Chợ Rẫy từ tháng 3/2021 đến tháng 3/2023. Kết quả: Chúng tôi ghi nhận được 92 bệnh nhân được chẩn đoán xác định VPBV do tụ cầu kháng methicillin, trong đó, có 54 (58,7%) điều trị thành công, 38 (41,3%) điều trị thất bại. Có sự khác biệt có ý nghĩa thống kê giữa nhóm điều trị thất bại và điều trị thành công trong các yếu tố sau: tuổi trung bình (64,3 ± 12,4 so với 58,3 ± 18,3), VPBV mức độ nặng (94,7% so với 74,1%), suy hô hấp (94,7% so với 72,2%), nhiễm trùng huyết (86,8% so với 33,3%), sốc nhiễm khuẩn (76,3% so với 14,8%), thở máy (97,4% so với 25,9%), lọc thận (50% so với 13%)
với p <
0,05. Kết luận: VPBV do tụ cầu kháng methicillin có liên quan đến tỷ lệ thất bại điều trị cao, cần phải đánh giá các yếu tố nguy cơ dẫn đến thất bại điều trị để chủ động điều trị và tiên lượng bệnh nhân.

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