In the year 2010, Research Institute for Marine Fisheries were cary out research, assessment the resource status of giant clams (Tridacnidae family) in 8 Vietnamese islands that included: Phu Quoc, Con Dao, Phu Qui, Hon Cau, Nam Yet, Nha Trang Bay, Ly Son and Cu Lao Cham. The results showed that in recent years, the authors found 03 main giant clam species, such as: Tridacna squamosa, T. maxima and T. crocea. Distribution of giant clam species are high fluctuation and different between islands, depth levels, structure of coral reefs and zone of reefs. Mecln of density highest species is Tridacna crocea (59 inds/500m2), T. maxima (1,7 inds/500m) and Tridacna squamosa (0,4 inds/500m2). Total biomas of 03 species in 08, above islands are aprroximately 1.717 tons (per 5.396 m2 coral reef areas). Maximum Stable Yield (MSY) of all 03 giant clam species is about 859 tons per year (suitable size for exploitation). Besides above results, base on other results ũ biological characteristics, ecology, distribution, status of exploitation and trade, the author proposed some solutions for conservation and development of giant clams species in Vietnam sea.