Health staff working for hospitals frequently has been facing with multiple occupational risks that may lead to stress, anxiety and depression. However, there is a dearth of research on these mental health issues in both public and private hospitals. This study aims to describe the prevalence of stress, anxiety and depression among health staff working in clinical departments of Vinh City General Hospital (public hospital) and Nghe An 115 Genral Hospital (private hospital). This is a study applying cross-sectional design. Data were collected by using self-administration questionnaire with all clinical health staff (221 participants) in this two hospitals. DASS 21 was used to screen symptoms of stress, anxiety and depression. Data were entered by using Epi Data 3.1 and analysed with SPSS 16.0. The study reveals that prevalence of stress, anxiety and depression among health staff in these two hospital are 20,4 percent, 29,0 percent and 13,6 percent, respectively. The prevalence of these mental health problems are not significantly different between these two hospitals. There are a small number of health staff having these symptoms at serious and very serious levels with stress: 0,5 percent and 0,5 percent
anxiety: 2,3 percent and 0,9 percent
and depression: 0 percent and 0,5 percent, respectively. It is necessary to screen for these mental health problems when periodically conducting medical check up for all health staff working in hospitals so as appropriate supports, counseling and changes of working environment would be provided in time to care and improve comprehensive health for health professionals.