Reason study: "Bu yang huan wu" (BDHN) are more promising in the treatment of complications of diabetes mellitus, so the authors tested all study drugs on early stages of diabetic nephropathy. Main results: Patients age (60 - 69) of control group of are 40 percent and 56 percent in BDHN group. Disease duration from 0 - 5 years accounted for 23.3 percent, primarily renal complications in stages 2 and 3. Blood pressure and body weight did not change during treatment. After 30 days of treatment BDHN group reduces proteinuria 72.12 percent (P 0.01), increase in HDL-C was 33.68 percent (P 0.01), LDL-C decreased 19.54 percent (P 0, 01) and reduce blood glucose. Liver function, renal function did not change. The main conclusion: Medicinal BDHN support effective in the treatment of early stage of diabetic nephropathy.