The aim of study is to evaluate toxicity and bactericidal capacity of the Ceri nitrat 0,04 M solution. Results indicated that no acute toxic signs/mortality was observed with orally dose of 2glkg rats body weight. In the sub-acute study, the solution CN 0,04 M (n=10) were administered once daily for 28 days to rats at the dose of 1 glkg, orally. No toxic signs/mortality was observed. There were no significant changes (p 0.05) in the haemato-biochemical, liver, spleen and kidney parameters. CN 0,04 M has fully bactericidal capacity on Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli species after 6 hours application with concentration dilution of 1/4 of original dose and after applying 24 hours with concentration dilution of 1/128 of original dose. At the concentration dilution of 1/8 original dose, the solution has fully bactericidal capacity on Escherichia coli and Staphylococcus aureus after 6 hours of application.