Background and Objective: Lymphedema complicating breast cancer treatment remains a challenging problem. The purpose of this study was to analysis of Iymphaticovenualar for treatment of upper limb lymphedema in breast cancer patients. Patients and Methods: 50 patients with upper extremity lymphedema secondary to treatment breast cancer underwent Iymphticovenular anastomoses using "Supermicrosurgical technique". These apatients were also divided two groups. Group I included patients of stage 1,2,3 and group II are patients of stage 3,4. Histological have been studied in 10 patients of group 1 and 10 patients of group II. Evaluation included qualitative assessment quantitaive circumferential analysis before and postoperation and follow up over six months at position upper wrist 5cm, velow elbow 5cm and upper elbow 5cm. Results: In groupll, skin and under tissue appeared fibrosis from light to severe, lymphatic trunks included tunica media, endothelial cell and smooth muscle also injuries. However, in group I it is almost fine. The circumference decreased at a week with means were V1: 6,44 +/- 0,41 cm
V2: 5,09 +/- 0,47 cm
V3: 6 +/- 0,52, respectively. The mean number of anastomoses performed per patient was mean of 3.44, and the diameter of vessels ranged from 0.3 to 1 mm. The mean operarive time was 3 hours. The mean follow-up time was six months with 91.67 percent good
8.33 percent fine and 0 percent poor. Conclusion: Lymphaticovenular anastomoses is effective reduce the severity of lymphedema in beast cancer patients. Long-term analysis is need.