Objectives: Acute calculous cholecystitis is one of most common reason for emergency admisson in surgical practice. Laparoscopic cholecystectomy is becoming popular for the treatment of calculous gallbladder disease. This approach is recently indicated for the definitve treatment of acute calculous cholecystitis in Khanh Hoa General Hospital. The purpose of this study was to evaluate the early outcomes, the safety and the feasibility of early laparoscopic cholecystetomy for acute calculous cholecystitis. Methods: The study was performed in 31 patients who had been diagnosed with acute calculous cholecystitis and early operated by laparoscopic approach between January 2013 and Mai 2014 in Khanh Hoa General Hospital. The study design is observational and prospective. Results: The average age was 53.42 +/- 15.36 y.o. 32.3 percent male, 67.7 percent female, male: female ratio was 1 : 2,1. The grade I of acute cholecystitis accounted for 87.1 percent and grade II for 12.9 percent. The average time from the admission to hospital until cholecystectomy was 3.22 +/- 1.63 days. The average time of operation was 78.23 +/- 24.75 minutes. The average length of total hospital stay was 8.55 +/- 2.45 days. There was no significant difference of these times between grade I and grade II groups. The conversion rate was 1/31 (3.23 percent). The early postoperative complication rate was 1/31 (3.23 percent). There was no death. Any late postoperative complication was noted. Conclusions: Early laparoscopic cholecystectomy is a safe, effective and feasible procedure for the treatment of acute calculous cholecystitis in Khanh Hoa General Hospital.