Cigarette and tobacco smoking is responsible, by its culmulative. effect, of high frequency of chronic obstructive pulmonary disease (COPD) as well as many other cardiovascular and metabolic diseases. Assessment of COPD is based on the level of symptoms, the risk of exacerbations, the severity of the spirometric abnormalities and identification of comorbidities, including cardiovascular and metabolic ones. Patients hospitalized for exacerbations of COPD are usually in serious or even life-thmatening conditions with incmased mortality. During acute exacerbations, patients with COPD, whether or not with cor pulmonale, likely to have increased cardiac load and altemd cardiac function. Them are still questions about the causes of mortality, prognostic or hospitalization conditioning indicators, diagnostic tools, optimal therapeutic supports during patients' exacerbations. This study addmsses one of these issues by identifying potential associations between the concentration of troponin I and some other parameters including comorbid conditions as well as some critical clinical and biological parameters.