Boi mau qua lau contains components that can lower blood glucose level. The aim of this research is to investigate the hypoglycemic action of the extract "Boi mau qua lau" in type 2 - like diabetic mice. The research was conducted by combining high fat diet for 9 weeks and low dose streptozotocin induced type 2 diabetes in mice. The chemicals used are streptozotocin 100 mg/kg bw Lp route, gliclazid 80 mg/kg bw, "Boi mau qua lau" 4.84g/kg, 19.36 g/kg bw, oral route, for 2 weeks. "Boi mau qua lau" has a glucose - lowering effect in type 2 diabetic mice after 2 weeks treatment, 26.64 percent at dose 4.84g/kg bw and 35.4 percent at dose 19.36g/kg bw (p 0.05).