Increase in hematoma volume (HV) in the brain after intracerebral hemorrhage (ICH) is a major cause of worsening clinical condition, and is an independent predictor for mortality and outcome. the goals were to evaluate the relationship between subclinical, clinical factors to change intracerebral HV in acute supratentorial hemorrhage in first 72 hours after onset. Descriptive, prospective analysis of 188 acute supratentorial hemorrhage patients associated With hypertension at admission, admitted within six hours afteronset, from 2010 to 2013. Results: The average age was 58.2, including 128 males (68 percent) and 60 females (32 percent). Univariate analysis showed that 9 important factors related to increased HV wef9: (1) Glasgow on admission, (2) NIHSS on admission, (3) Rankin at admission, (4) SBP at admission, (5) Hematoma volume, (6) Shape of hematoma, (7) Spot, sign, (8) WBC, and (9) Glycemie. Multivariate analysis showed that two independent prognostic factors associated with increasing HV were: (1) The shape of the hematoma is irregular on CT, and (2) Spot sign on CTA.