Microcapsules have many applications in the technical textile field. For recent ten years, there have been a lot of researches to mention the microencapsulation process and the impregnation conditions. Nevertheless, there have been few studies referring the optimum specification of support fabrics. This work studied the influence of woven structure and yarn density on microcapsule loading capability of fabric, used for medical textile application. the authors investigated on two fabric groups. Group G1 has three kinds of TC83/17 fabric woven with 1/1, 2/1 and 3/1 structure. Group G2 is 2/1 cotton fabric woven with four levels of weft yarn density 85, 88, 90 and 93 yarn/inch. By using scanning electron microscope SEM, evaluating the weight change and air resistance change after microcapsule treatment, the results show that among investigated fabrics, the one with density of 85 yarn/inch can absorb maximum content of microcapsules and the woven structure 2/1 is the best one for support fabric.