BACKGROUND: Acute kidney injury (AKI) is one of the poor prognosticating conditions in the intensive care unit (ICU). It increases mortality. Its pathophysiology involves various aspects, such as prerenal, renal, and postrenal components. Many times, it is a combination of one or more etiologies. Its management is a challenge, as no agent is approved for its prevention or treatment. It is the comprehensive treatment and timely institution of renal replacement therapy (RRT) that matter most. To understand the prognosis and outcome of patients with AKI, we conducted this observational analytical study. MATERIALS AND METHODS: It was a observational study. To analyze the effect of loop diuretics, we grouped the patients into two: one group received furosemide, and the other did not. RESULTS: There was a male preponderance among AKI patients. Hypertension and diabetes were the most common comorbidities. About 44.1% of patients received diuretics. There was no significant difference among patients in the requirement for RRT or the need for vasopressors
however, the outcome of patients who received diuretics was worse. CONCLUSION: The use of diuretics did not improve the outcome of acute kidney injury.