Lung Cancer Screening and Incidental Findings: A Research Agenda. An Official American Thoracic Society Research Statement.

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Tác giả: Abbie Begnaud, Farouk Dako, Kwun M Fong, Michael Gieske, Louise M Henderson, Kimberly Kallianos, Roger Y Kim, Stephen Lam, Pyng Lee, Mary Pasquinelli, Ilana Richman, M Patricia Rivera, Lori C Sakoda, Ronald G Schwartz, Robert A Smith, Nichole T Tanner, Lynn T Tanoue, Matthew Triplette, Emily B Tsai, Joseph Yeboah

Ngôn ngữ: eng

Ký hiệu phân loại: 344.0955 Labor, social service, education, cultural law

Thông tin xuất bản: United States : American journal of respiratory and critical care medicine , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 51213

BACKGROUND: Lung cancer screening with low-dose computed tomography (LDCT) may uncover incidental findings (IFs) unrelated to lung cancer. There may be potential benefits from identifying clinically significant IFs that warrant intervention and potential harms related to identifying IFs that are not clinically significant but may result in additional evaluation, clinician effort, patient anxiety, complications, and excess cost. OBJECTIVES: To identify knowledge and research gaps and develop and prioritize research questions to address the approach to and management of IFs. METHODS: We convened a multidisciplinary panel to review the available literature on IFs detected in lung cancer screening LDCT exams, focusing on variability and standardizing reporting, management of IFs, and evaluation of the benefits and harms of IFs, particularly cardiovascular-related IFs. We used a three-round modified Delphi process to prioritize research questions. RESULTS: This statement identifies knowledge gaps in (1) reporting of IFs, (2) management of IFs, and (3) identifying and reporting coronary artery calcification found on lung cancer screening LDCT. Finally, we present the panel's initial 36 research questions and the final 20 prioritized questions. CONCLUSIONS: This statement provides a prioritized research agenda to further efforts focused on evaluating, managing, and increasing awareness of IFs in lung cancer screening.
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