Despite advances in wound treatment through tissue engineering, the rapid colonization of biomaterials by host cells remains a crucial step toward complete wound healing. Thanks to their excellent biocompatibility, biodegradability, low antigenicity and cost-effectiveness, cross-linked hydrogels have attracted much attention as a viable solution for wound treatment. In this work, we have developed an inovative cross-linking method for gelatin-based hydrogels inspired by the wound closure mechanism of the green algae