Three-component reactions of conjugated dienes, CH acids and formaldehyde under diffusion mixing conditions.

• Tác giả: Eugene V Babaev, Elena K Beloglazkina, Maxim E Kukushkin, Dmitry E Shybanov, Nikolai V Zyk
• Ngôn ngữ: eng
• Thông tin xuất bản: Germany : Beilstein journal of organic chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 52001

Tóm tắt

A diffusion mixing technique with a volatile reagent was successfully used to generate crotonic condensation adducts of active methylene compounds and formaldehyde at room temperature in the absence of strong acids and bases. The formed adducts were highly reactive intermediates capable of reacting with dienes in a three-component reaction, leading to the formation of Diels-Alder main reaction products.