Highly efficient combination of multiple single cells using a deterministic single-cell combinatorial reactor.

• Tác giả: Teruo Fujii, Kunihiko Iizuka, Soo Hyeon Kim, Saori Tago, Mina Yoshida
• Ngôn ngữ: eng
• Ký hiệu phân loại: 415.54 Nouns
• Thông tin xuất bản: England : Lab on a chip , 2025
• Bộ sưu tập: NCBI
• ID: 52491

Tóm tắt

Compartmentalization of multiple single cells and/or single microbeads holds significant potential for advanced biological research including single-cell transcriptome analysis or cell-cell interactions. To ensure reliable analysis and prevent misinterpretation, it is essential to achieve highly efficient pairing or combining of single objects. In this paper, we introduce a novel microfluidic device coupled with a multilayer interconnect Si/SiO