Optimized synthesis of biphasic calcium phosphate: enhancing bone regeneration with a tailored β-tricalcium phosphate/hydroxyapatite ratio.

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Tác giả: Ngoc Thuy Trang Le, Anh Phuong Nguyen Hong, Dai Hai Nguyen, Thi My Huyen Nguyen, Hyun-Ji Park, Ki Dong Park, Qui Thanh Hoai Ta, Dieu Linh Tran, Manh Hoang Tran

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: England : Biomaterials science , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 52616

Biphasic calcium phosphate (BCP) is a bioceramic widely used in hard tissue engineering for bone replacement. BCP consists of β-tricalcium phosphate (β-TCP) - a highly soluble and resorbable phase - and hydroxyapatite (HA) - a highly stable phase, creating a balance between solubility and resorption, optimally supporting cell interactions and tissue growth. The β-TCP/HA ratio significantly affects the resorption, solubility, and cellular response, with a higher β-TCP ratio increasing resorption due to its solubility. BCP is commonly synthesized by calcining calcium-deficient apatite (CDA) at temperatures above 700 °C
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