Đánh giá hiệu quả bơm rửa mũi với dung dịch budesonide sau phẫu thuật nội soi mũi xoang trên bệnh nhân viêm mũi xoang mạn có polyp mũi

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Tác giả: Viết Luân Trần, Mỹ Thục Uyên Trương

Ngôn ngữ: vie

Ký hiệu phân loại: 616.21 *Diseases of nose, nasopharynx, paranasal sinuses, larynx

Thông tin xuất bản: Y học Việt Nam, 2017

Mô tả vật lý: 272-275

Bộ sưu tập: Metadata

ID: 534878

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Đánh giá hiệu quả bơm rửa mũi với dung dịch budesonide sau phẫu thuật nội soi mũi xoang trên 45 bệnh nhân viêm mũi xoang mạn có polyp mũi điều trị tại bệnh viện Tai mũi họng từ 12/2016 đến 5/2017. Kêt quả cho thấy các triệu chứng cơ năng cải thiện rõ rệt sau 1 tháng và duy trì ổn định sau 3 tháng sử dụng bơm rửa mũi với dung dịch budesonide. Chưa ghi nhận tác dụng phụ do dùng corticoid kéo dài.Objective: to evaluate the efficacy of postoperative budesonide nasal irrigation in patents with chronic rhinosinusitis and nasal polyps. Method: Cross-sectional with clinical trial study. Patients with chronic rhinosinusitis with nasal polyps undenwent endoscopic sinus surgery, received budesonide nasal irrigation 1 week postoperative and continued in 3 months, in ENT hosptial, from 12/2016 to 05/2017. Results: 45 Patients with chronic rhinosinusitis and nasal polyps undenwent endoscopic sinus surgery, received budesonide nasal irrigation 1 week postoperative and continued in 3 months (twice a day, 240ml saline isotonic with 500ug budesonide). The clinical symptoms improved (SNOT 22 preoperative score= 48.9 ± 9.1, 1 month postoperative score = 14.5 ± 7.6
p <
0,001
3 month postoperative score = 10.5 ± 5,2
p <
0,001)
the endoscopic Lund-Mackay score (3 criteria: polyp, edema, secretion) preoperative 10.6 ± 2.7, decreased postoperatively 1 month = 2.9 ± 1.5
p <
0.001, 3 month = 1.4 ± 1.3
p <
0.001, No side effect with long-term corticoid using is recognized in our sutdy. Conclusion: Postoperative budesonide nasal irrigation in patients with chronic rhinosinusitis and nasal polyps improve the sinus healing, maintain the wide sinus ostium, reduce nasal adhesions and control the recurrence of nasal polyps.

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