Đánh giá yếu tố tiên lượng sống còn của bệnh nhân ung thư biểu mô tế bào gan điều trị đốt sóng cao tần

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Văn Long Đào, Việt Hằng Đào

Ngôn ngữ: vie

Ký hiệu phân loại: 571.45 *Radiobiology

Thông tin xuất bản: Y học Việt Nam, 2018

Mô tả vật lý: 137-141

Bộ sưu tập: Metadata

ID: 535082

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Chủ đề

Đánh giá yếu tố tiên lượng sống còn của 130 bệnh nhân ung thư biểu mô tế bào gan điều trị đốt sóng cao tần từ 10/2011 đến 6/2016 tại bệnh viện Bạch Mai. Kết quả cho thấy thời gian sống thêm toàn bộ trung bình là 48,5 tháng. Có 31 bệnh nhân tử vong trong quá trình theo dõi. Tỷ lệ bệnh nhân chết ước tính trung bình là 8,3/100 người theo dõi/năm. Không có sự khác biệt về tỷ lệ tử vong giữa các nhóm khác nhau về số khối, kích thước khối, loại kim, mức độ xơ gan.Hepatocellular carcinoma (HCC) is a common malignancy worldwide and in Vietnam. Radio-frequency ablation (RFA) is a local therapy to destroy tumor by heat, however, not many studies in our country have been conducted to analyze factors correlating to survival prognosis. This study was conducted to evaluate overall survival after 1 year, 2 years and 3 years and prognostic factors relating in HCC patients treated by RFA. This study was an interventional, follow-up study on 130 HCC patents stage Barcelona (BCLC) 0 and A treated RFA from Oct/2011 to June/2016 in Gastroenterology department of Bach Mai hospital with mean follow up time being 30.0 ± 11.1 months. Overall survival time was 48.5 months (CI 95%
44.7 - 52.4 months). 31 patents (23.8%) died during follow-up time with mean survival time being 33.6 months (CI 95%: 31,7-35,6 months). The estimated mean death rate was 8.3/100 follow-up patients/year. There was no difference of survival rate among different groups of number of tumors, tumor size, types of needles and liver cirrhosis severity. Cox regression analysis recorded past history of other therapies and response after 1 month had correlation with survival prognosis (p <
0,05 and r = 0,37). RFA is a curative therapy to improve overall survival
early response and past history of other therapies are survival prognosis factors for HCC patients treated by RFA.

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