Liên quan giữa nồng độ Glucagon-like peptide-1 với biến chứng thận ở bệnh nhân đái tháo đường type 2 chẩn đoán lần đầu

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Tác giả: Đình Tuân Lê, Thị Thu Nga Nguyễn, Thị Thanh Hóa Trần

Ngôn ngữ: vie

Ký hiệu phân loại: 616.462 Diabetes mellitus

Thông tin xuất bản: Nghiên cứu Y học, 2017

Mô tả vật lý: 26-33

Bộ sưu tập: Metadata

ID: 535790

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The paper identifies the relationship between the concentration of Glucagon-like peptide-1 and renal complications in 160 patients with type 2 diabetes first diagnosed at the Central Endocrinology Hospital. The results showed that the percentage of patients with microalbuminuria (MAU) (+) was 7.5%, macalbuminuria (MAC) (+) was 13.1%, Percentage of patients with decreased concentration of Glucagon-like peptide-1 in the body of complications, 2.24 times higher than the group without body complications. Multivariate analysis showed an increase in MAU levels was associated with a decrease in the concentration of Glucagon-like peptide-1 and hyperglycaemia when fasting. There was an association between the concentration of Glucagon-like peptide-1 and renal complications in patients with type 2 diabetes first diagnosed.Xác định mối liên quan giữa nồng độ Glucagon-like peptide-1 với biến chứng thận ở 160 bệnh nhân đái tháo đường type 2 chẩn đoán lần đầu tại bệnh viện Nội tiết Trung ương. Kết quả cho thấy tỷ lệ bệnh nhân có microalbumin niệu (MAU) (+) là 7,5%, macroalbumin niệu (MAC) (+) là 13,1%, Tỷ lệ bệnh nhân giảm nồng độ Glucagon-like peptide-1 ở nhóm có biến chứng thân cao hơn 2,24 lần so với nhóm không có biến chứng thân. Phân tích đa biến cho thấy tăng nồng độ MAU có liên quan với giảm nồng độ Glucagon-like peptide-1 và tăng glucose máu khi đói. Có mối liên quan giữa nồng độ Glucagon-like peptide-1 với biến chứng thận ở bệnh nhân đái tháo đường type 2 được chẩn đoán lần đầu.

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