Nghiên cứu sự biến đổi một số chỉ số hóa sinh máu của chuột nhiễm độc chì acetat bán trường diễn và tác dụng của sâm Ngọc Linh sinh khối

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Thanh Xuân Nguyễn, Văn Bằng Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại: 612.11822 Blood and circulation

Thông tin xuất bản: Y học Việt Nam, 2017

Mô tả vật lý: 203-208

Bộ sưu tập: Metadata

ID: 536552

Thêm vào giỏ

Tóm tắt
Chủ đề

Objectives: study the change of some blood biochemical indexes of mice with subchronic lead toxication and effect of Ngoc Linh ginseng mass. Subjects and methods: 120 male white house-mice, 20 - 25 gram (12 mice were killed and taken blood to expenment immediately pnor to testing). 108 mice infected lead acetate (20 mg/kg/day), on date of 15, 30, 45
divided into 3 lots: control lot (36 mice: lot 1)
lot infected lead acetate (36 mice: lot 2)
lot infected lead acetate and drinking with NLG M to protect (36 mice: lot 3) and study effect of Panax vietnamensis biomass solution (375 mg/kg/day). Results: activity of ALT, AST, GGT of lot 2 is higher than lot 1 in the same time (p<
0.05)
iot 3 (56.78 ± 9.75
291.0 ± 59.5
3.10 ± 0.98 U/L) is lower than lot 1 on date of 45 (66.14 ± 10.85
351.9 ± 64.6
4.26 ± 1.09 U/L) (p<
0.05). Lot 2: total bilirubin, ure on date of 45 (4.26 ± 1.09 pmol/L
3.02 ± 0.32 mmol/L) is higher than experiment immediately pnor to testing (3.18 ± 1.15 pmol/L
2.75 ± 0.27 mmol/L) and lot 1 (3.20 ± 1.14 pmoL/L
2.78 ± 0.16 mmol/L) (p<
0.05). Lot 2: ereabnin on date of 30,45 is higher than lot 1, on date of 45, creatinin is higher than experiment immediately prior to testing (p<
0.05). Conclusion: activity of plasma ALT, AST, GGT
concentration of ure, creatinin of lot infected lead acetate is higher than control lot (p<
0.05)
activity of plasma ALT, AST, GGT of lot infected lead acetate and dnnking with NLG M to protect is lower than lot infected lead acetate (p<
0.05).Xác định sự biến đổi một số chỉ số hóa sinh máu ở chuột nhắt bị gây độc chì acetat bán trường diễn và tác dụng của sâm Ngọc Linh sinh khối. 108 chuột được gây độc, chia làm 3 lô. Lô chứng, lô gây độc và lô gây độc có sử dụng sâm Ngọc Linh. Kết quả cho thấy hoạt độ AST, ALT, GGT huyết tương, nồng độ ure, creatinin máu ở lô chuột gây độc cao hơn lô đối chứng. Hoạt độ AST, ALT, GGT huyết tương ở lô gây độc có uống sâm Ngọc Linh sinh khối thấp hơn lô gây độc không uống sâm Ngọc Linh sinh khối.

Tạo bộ sưu tập với mã QR