Nồng độ NT-ProBNP huyết tương có giá trị chẩn đoán suy tim trên bệnh nhân suy thận mạn giai đoạn cuối có lọc máu chu kỳ

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Tác giả: Thị Tuấn Nguyễn, Thị Thanh Thủy Phạm

Ngôn ngữ: vie

Ký hiệu phân loại: 544.5 Qualitative analysis

Thông tin xuất bản: Sinh lý học Việt Nam, 2017

Mô tả vật lý: 21-27

Bộ sưu tập: Metadata

ID: 536910

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Identify the role of NT-proBNP testing in heart failure diagnosis and to determine the association between NT-proBNP and grading of heart failure in patients, with chronic renal failure, who were having periodic dialysis. Subject and method: Crosssectional study of 76 patients. Result: The best cut point of the concentration of NT-proBNP which has diagnostic value for heart failure in patients with chronic renal failure, who were having periodic dialysis is 1802 pg/ml (NT-proBNP testing had a sensitivity of 88.64% and a specificity of 84.37%, area under the curve AUC is 0.045). NT-proBNP concentration increases with the level of heart failure: Level I (2706.25 ± 1314.36 pg/ml). level II (8098.77 ± 4523.40 pg/ml), level III (14748.50 ± 9012.24 pg/ml) and level IV, (30843.50 ± 9902.04 pg/ml). Conclusion: There are positive correlation between the concentration of NT - proBNP and the level of heart failure.Xác định nồng độ NT-ProBNP huyết tương trên 119 người, trong đó có 43 người bình thường, 32 bệnh nhân suy thận nhưng không suy tim và 44 bệnh nhân suy tim và suy thận. Kết quả cho thấy nồng độ NT-ProBNP tăng dần theo mức độ suy tim và có mối tương quan thuận giữa nồng độ NT-ProBNP và phân độ suy tim.

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