Phân tích trình tự vùng gen ty thể HV1 và HV2 trên dân tộc Chăm Việt Nam

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Tác giả: Huy Thịnh Trần, Thị Thúy Hằng Trần, Vân Khánh Trần

Ngôn ngữ: vie

Ký hiệu phân loại: 495.97 Languages of East and Southeast Asia Sino-Tibetan languages

Thông tin xuất bản: Nghiên cứu Y học, 2017

Mô tả vật lý: 45519

Bộ sưu tập: Metadata

ID: 536998

Thêm vào giỏ

The article identifies the sequence and analysis of single nucleotide polymorphisms in the mitochondrial genome HV1 and HV2 in the Cham ethnic group of Vietnam. The results showed that a complete sequence of the HV1, HV2 genome was identified and many SNPs were detected in the study samples. Determining the rate of some common SNPs: SNP A73G and A263G, 315msC met 100% of the research sample, 309insC was 64%, T16189C was 56%, A16183C was 44%, C16223T was 37%, G16129A was 23%, T16304C 21%, C16261T is 20%, C150T is 20% and A210G is 20%. This is the first and complete data on the sequence of mitochondrial genome HV1. HV2 of Cham people with relatively large number of samples.Xác định trình tự và phân tích đa hình nucleotid đơn vùng gen ty thể HV1 và HV2 trên dân tộc Chăm Việt Nam. Kết quả cho thấy đã xác định được trình tự hoàn chỉnh vùng gen HV1, HV2 và phát hiện được nhiều SNP ở các mẫu nghiên cứu. Xác định được tỷ lệ một số SNP hay gặp: SNP A73G và A263G, 315msC gặp 100% mẫu nghiên cứu, 309insC là 64%, T16189C là 56%, A16183C là 44%, C16223T là 37%, G16129A là 23%, T16304C là 21%, C16261T là 20%, C150T là 20% và A210G là 20%.. Đây là số liệu đầu tiên, hoàn chỉnh về trình tự vùng gen ty thể HV1. HV2 của dân tộc Chăm với số lượng mẫu tương đối lớn.

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