Tác động của thông khí tần số thấp và thể tích khí lưu thông thấp lên các dấu ấn viêm hệ thống trên bệnh nhân chạy máu tuần hoàn ngoài cơ thể phẫu thuật bắc cầu chủ vành

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Tác giả: Ngọc Sơn Đỗ, Mai Hương Hà, Quốc Chính Lương, Thị Dụ Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại: 612.23 Human physiology

Thông tin xuất bản: Nghiên cứu Y học, 2017

Mô tả vật lý: 63-71

Bộ sưu tập: Metadata

ID: 537394

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Tác động của thông khí tần số thấp và thẻ tích khí lưu thông thấp lên các dấu ấn viêm hệ thống trên bệnh nhân chạy máu tuần hoàn ngoài cơ thể phẫu thuật bắc cầu chủ vành tại Bệnh viện Tim Hà Nội từ 2015 đến 2016. Tổng số 61 bệnh nhân được chia làm 2 nhóm, nhóm can thiệp có 31 bệnh nhân được thông khí nhân tạo tần số thấp và nhóm chứng có 30 bệnh nhân không thông khí nhân tạo. Kết quả cho thấy nồng độ IL6 ở thời điểm 6 giờ, 24 giờ, 48 giờ sau chạy máy tuần hoàn ngoài cơ thể của nhóm can thiệp thấp hơn nhóm chứng. CRP ở thời điểm 48 giờ sau phẫu thuật của nhóm can thiệp thấp hơn nhóm chứng. Không có sự khác biệt về nồng độ procalcitoni ở các thời điểm giữa 2 nhóm. Điểm cutoff chẩn đoán viêm phổi của procalcitoni là procalcitonin ia 4,8 ng/mi với độ nhậy 75% và độ đặc hiệu 94,1%.The paper shows the effect of low frequency ventilation and low air flow card on systemic markers on blood circulation patients outside coronary bypass surgery at Hanoi Heart Hospital from 2015. By 2016. A total of 61 patients were divided into 2 groups, the intervention group had 31 patients with low frequency artificial ventilation and the control group had 30 patients with artificial ventilation. The results showed that IL6 concentration at 6 hours, 24 hours, 48 hours after the circulating machine outside the body of the intervention group was lower than the control group. CRP at 48 hours after surgery of the intervention group was lower than the control group. There is no difference in the concentration of procalcitoni at the time between the two groups. The cutoff diagnosis of pneumonia of procalcitoni is procalcitonin at 4.8 ng / mi with 75% sensitivity and 94.1% specificity.

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