Phân lập và xác định đặc tính di truyền của virus gây bệnh ca-rê trên chó nuôi tại thành phố Hồ Chí Minh=Isolation and genetic analysis of Canine distemper virus (CDV) in domestic dogs in Ho Chi Minh City, Viet Nam

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Tác giả: Chiến Vũ Kim, Dũng Nguyễn Văn, Phan Xuân Thảo

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Khoa học kỹ thuật Thú y, 2018

Mô tả vật lý: tr.19

Bộ sưu tập: Metadata

ID: 541073

Thêm vào giỏ

CDV is one of the most serious pathogens found in many carnivorous animal species, includingdomestic dogs. In this study, H gene of CDV were detected in five domestic dogs, Viet Namese breed,suffering with diarrhea. There were two, out of the identified CDVs from the positive dogs with H genessuccessfully isolated. The complete genome of one isolated virus, CDV/dog/HCM/33/140816, wasdetermined. The result of phylogenetic analysis showed that all the Viet Namese CDVs belonged tothe Asia-1 genotype. In addition, the result of analyzing the isolated CDVs indicated the H proteins ofViet Namese CDV strains were highly similar in comparison with those of the Chinese CDVs (98.4%to 99.3% identity). These results indicated that the Asia-1 genotype of CDV was the predominantgenotype circulating among the domestic dog population in Ho Chi Minh City. It is indicated thattransboundary transmission of CDVs may be occurred between Viet Nam and China.Virus gây bệnh Ca-rê (CDV) là một trong những tác nhân gây bệnh nghiêm trọng trên nhiều loài thúăn thịt, bao gồm cả chó nuôi. Trong nghiên cứu này, gen H của CDV được phát hiện trên 5 con chó nuôibị bệnh tiêu chảy thuộc giống chó Việt Nam và hai trong số các chủng CDV phát hiện được phân lậpthành công. Toàn bộ bộ gen của một chủng phân lập, CDV/dog/HCM/33/140816, đã được phân tích. Kếtquả phân tích cây phát sinh dòng cho thấy các chủng CDV Việt Nam đều thuộc genotyp Asia-1. Hơn nữa,kết quả phân tích cho thấy mức tương đồng protein H của các chủng phân lập và của các chủng CDV từTrung Quốc là khá cao (98,4% đến 99,3%). Kết quả của nghiên cứu này cũng cho thấy genotyp Asia-1là genotyp chính đang lưu hành trên chó nuôi tại Thành phố Hồ Chí Minh và sự truyền lây của CDV quabiên giới giữa Việt Nam và Trung Quốc có thể đã xảy ra.

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