Objective: To evaluate effects on some hemodynamic variables in septic shock patients of continuous veno-venous heamofiltration (eVVH). Subject: 52 septic shock patients were enrolled to study, was treated following sse 2008 guidelines, inserted Swan-Ganz catheter and supported by eVVH. Study method: intervention and comparison. Result: The mean of pulse rate, mean blood pressure, SVR at the time starting CVVH were 127 +/- 19.6 beats/min, 71 +/- 9.4 mmHg, 840 +/-310 +/-399 dynes/see/ems changing to 107 +/-26 beat/min, 83 +/-14.2 mmHg and 1091 +/-399 dynes/see/ems at the time CVVH finishing (p 0.001). CO, CI and SV were maintained stably during the CVVH process in the survivor group with CO, CI and SV at the time CVVH starting were 6.6+/-2.38 L/min, 4.2 +/- 1.54 L/min/m2 va 60.6 +/- 16.52 ml changing to 6.1 +/- 1.42 /min, 4.0 +/- 1.00 L/min/m2 va 58.9 +/- 15.78 ml at the time CVVH finishing (p 0.05), recovering time from shock was 58 +/- 31,7 hours, recovering rate from shock was 71.3 percent. Conclusion: CVVH helps reducing high pulse rate, elevating mean blood pressure and SRV in septic shock patients, for the survivor group CVVH helps maintaining CO, CI and SV stably.