Patients and Methods: The study involved 78 patients in whom SBE was performed for small bowel bleeding at Bach Mai Hospital during the period June 2011 through June 2014. All patients had already undergone standard upper-GI and lower-GI endoscopy at hospital. Results: Efficient diagnosis of small bowel bleeding by small bowel endoscopy were 71.8 percent. The source of bleeding identified in the small bowel were as follows: polyp (23.2 percent), ulcerative lesion (35.6 percent), tumor (16.0 percent), Meckel's diverticulum (5.5 percent), vascular lesion (7.1 percent), small bowel diverticulosis (5.5 percent) and inflammation of small bowel caused by the parasite (7.1 percent). The treatment were as follows: medical treatment (48.2 percent), endoscopic treatment (30.4 percent) and surgery (21.4 percent). Conclusion: Endoscopic small bowel is highly effective in the diagnosis and treatment of patients with small bowel bleeding.