Sinh thái dịch tễ học cúm A/H5 tại Quảng Bình=Ecological epidemiology of Avian influenza H5 in Quang Binh

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Tác giả: Phạm Minh Hằng

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Khoa học kỹ thuật Thú y, 2018

Mô tả vật lý: tr.18

Bộ sưu tập: Metadata

ID: 544835

Thêm vào giỏ

Sự xuất hiện và lây truyền virus cúm gia cầm (AIV) vẫn là các vấn đề quan trọng đối với động vật hoang dãvà sức khoẻ con người ở nhiều nơi trên thế giới. Sự bùng phát và lưu hành của virus này đã được nghiên cứu trongcác hệ sinh thái khác nhau. Tuy nhiên, các yếu tố quyết định về sinh thái liên quan đến nguy cơ cúm gia cầm độclực cao (HPAI) được cho là sự khác nhau về các điều kiện sinh thái nông nghiệp, môi trường, địa lý và các yếutố nguy cơ. Nghiên cứu này nhằm mục đích phân tích đặc điểm sinh thái dịch tễ cúm A/H5 ở Quảng Bình năm2016 để tìm ra các giải pháp can thiệp phòng dịch tốt hơn. Kết quả nghiên cứu cho thấy 2 yếu tố như số giờ nắngvà chim hoang giã có liên quan chặt chẽ đến huyết thanh dương tính và sự lưu hành của virus cúmA/H5 ở QuảngBình. Năm chủng virus H5N6 được phát hiện tại Quảng Bình có mức tương đồng với các chủng H5N6 phát hiệntại Việt Nam (89-99%) và các nước khác (96-97%). Phân tích phả hệ cho thấy những chủng virus này thuộc clade2.3.4.4C và có quan hệ gần với các chủng virus cúm gia cầm H5N6 gần đây được phát hiện ở Việt Nam, TrungQuốc, Hàn Quốc và Nhật Bản. Việc kết hợp các giải pháp kỹ thuật bao gồm hạn chế các yếu tố nguy cơ, tiêmphòng, giám sát sau tiêm phòng, nâng cao hiểu biết về CGC của người chăn nuôi có thể giảm sự lây nhiễm virusA/H5 vào đàn gia cầm ở mức hộ chăn nuôi.The occurrence and transmission of Avian influenza virus (AIV) are still important issues to the wildlifeanimals and human health in many places around the world. The outbreaks and circulations of this viruswere studied in different ecological systems. However, the ecological determinants associated with risk ofhighly pathogenic avian influenza (HPAI) which was considered as the differences on the geographical,environmental, agricultural ecology conditions and the risky factors. This study aimed to characterize theecological epidemiology of avian influenza virus H5 in Quang Binh province in 2016 so as to find out thebetter intervention solutions in HPAI H5 epidemic prevention. The studied results showed that 2 factors,such as sunlight hour number and wildlife birds related closely to avian influenza A/H5 sero-prevalenceand avian influenza virus circulation in Quang Binh province. There were 5 avian influenza A (H5N6)virus strains detected in Quang Bình having similarity level of HA gene sequence up to 89-99% incomparison with those of H5N6 virus strains isolated in Viet Nam and 96-97% with the isolates in othercountries. Genetic and phylogenetic analyses revealed that these viruses were classified into the geneticclade 2.3.4.4C and were closely related to HPAI (H5N6) viruses that recently detected in Viet Nam,China, South Korea and Japan. Combination of the technical solutions including reduction of the riskyfactors, vaccination, surveillance in post-vaccination, improvement on the avian influenza knowledge forthe poultry farmers could reduce the transmission of avian influenza virus at the farm levels.

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